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HRID 2227663作成日：2026年10月27日

Carbonochloridic acid, octyl ester → ethyl 3-[[1-methyl-2-[[N-methyl-4-(N-octoxycarbonylcarbamimidoyl)anilino]methyl]benzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate

https://huagongshe.com/reaction/2227663

反応式

関与物質

役割名称HCID仕込み量
反応物Carbonochloridic acid, octyl esterHCID 81956—
反応物1-methyl-2-[N-(4-amidinophenyl)-N-methylaminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide hydrochlorideHCID 18412298—
生成物ethyl 3-[[1-methyl-2-[[N-methyl-4-(N-octoxycarbonylcarbamimidoyl)anilino]methyl]benzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoateHCID 140409596—

反応手順

Prepared analogously to Example 90 from 1-methyl-2-[N-(4-amidinophenyl)-N-methylaminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide hydrochloride and n-octyl chloroformate.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06414008B1
出典データセットuspto-grants-2002_07
ORD IDord-8c6e05832e724e9599ee1a485da57aa3
出典メモuspto-grants-2002_07