Sodium Methoxide → HCID 86758338、化合物
反応式
C[O-].[Na+].[CH3:4][O:5][CH:6]=[C:7]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[CH:18]([O:20][N:21]=[CH:22][C:23](=[N:28][O:29][CH3:30])[CH2:24][C:25]([CH3:27])=[CH2:26])[CH3:19])[C:8]([O:10][CH3:11])=[O:9]>>[CH3:4][O:5][CH:6]=[C:7]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[CH:18]([O:20][N:21]=[CH:22][C:23](=[N:28][O:29][CH3:30])[CH:24]=[C:25]([CH3:26])[CH3:27])[CH3:19])[C:8]([O:10][CH3:11])=[O:9]参加物
3
反応条件
- 温度
- 23 °C
実験手順
4.9 g of solid sodium methoxide were added to 16.7 g of methyl 3-methoxy-2-[2-(2-methoxyimino-1,4-dimethylpent-4-enylideneamino-oxymethyl)phenyl]acrylate from Example 7, and the mixture was stirred at 23° C. for 1 hour. Work-up was carried out similarly to Example 6. Chromatographic purification over silica gel using cyclohexane/methyl tert-butyl ether (9:1) gave 7.1 g of the title compound as a colorless solid.
後処理
- customChromatographic purification over silica gel