化工社化工社 化学情報印刷レポート · 研究参考用
Water → HCID 178432777、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Ethyl 2-chloroacetoacetate | HCID 11858 | — |
| 反応物 | 2,2,2-Trichloroethanimidamide | HCID 35608 | — |
| 溶媒 | Cyclohexane | HCID 8078 | — |
| 生成物 | HCID 178432777 | HCID 178432777 | 31% |
反応手順
A mixture of 30.0 g (0.18 mole) trichloroacetamidine, 25.2 g (0.18 mole) potassium carbonate, 30.3 g (0.18 mole) ethyl 2-chloroacetoacetate, and 300 ml water was stirred 18 hours. The aqueous solution was decanted from heavier tars and acidified with hydrochloric acid. The precipitate that was formed was filtered, washed, and dried to give 14.7 g (31% yield; mp 130°-145° C.) of crude product. An analytical sample was prepared by recrystallization from cyclohexane (mp 156°-157° C.). The structure was confirmed via infrared and elemental analysis.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04352806 |
| 出典データセット | uspto-grants-1982_10 |
| ORD ID | ord-7fb745fa041a43c0a7da70058a57baa0 |
| 出典メモ | uspto-grants-1982_10 |