Hydrochloric Acid → 5-Aminoisothiazole-3,4-dicarbonitrile

HRID 2231960ノート

反応式

HRID 2231960 の反応式
CN(C)C=[N:4][C:5]1[S:9][N:8]=[C:7]([C:10]#[N:11])[C:6]=1[C:12]#[N:13].C(O)C.Cl>O>[NH2:4][C:5]1[S:9][N:8]=[C:7]([C:10]#[N:11])[C:6]=1[C:12]#[N:13]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 54385684HCID 54385684、化合物

生成物 1

HCID 212852515-Aminoisothiazole-3,4-dicarbonitrile収率 87%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A mixture of 45.3 parts of N,N-dimethyl-N'-(3,4-dicyanoisothiazol-5-yl)-formamidine, 400 parts of ethanol and 60 parts of concentrated hydrochloric acid is heated at the boil for 2.5 hours, after which it is introduced into 400 parts of water. The colorless precipitate is filtered off under suction, washed with water and dried to give 28.6 parts (87% of theory) of 5-aminoisothiazole-3,4-dicarbonitrile.

後処理

  1. temperatureis heated at the boil for 2.5 hours
  2. filtrationThe colorless precipitate is filtered off under suction
  3. washwashed with water
  4. customdried

出典と根拠

ORDレコード
ord-0cb5fe07597141849b590bf460fabdaf
出典データセット
uspto-grants-1988_11
特許番号
US04785116

反応ノート

読み込み中…