Hydrochloric Acid → 2-(2-Thienyl)thiazole
反応式
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([NH2:8])=[S:7].CO[CH:11](OC)[CH2:12]Br.Cl>C(O)C>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[S:7][CH:11]=[CH:12][N:8]=1参加物
5
実験手順
In a manner similar to Step B of Example 1, the reaction of 13.3 grams (0.027 mole) of (thien-2-yl)thiocarboxamide with 16.0 grams (0.0945 mole) of bromoacetaldehyde dimethyl acetal and 2 ml of concentrated hydrochloric acid in 250 ml of ethanol yielded 7.6 grams of 2-(thien-2-yl)thiazole as an oil.
出典と根拠
- ORDレコード
- ord-25610fb6de494cc089d6090a70ee6cbd
- 出典データセット
- uspto-grants-1988_11
- 特許番号
- US04788207
反応ノート
読み込み中…