Hydrochloric Acid → Imidazo[1,2-a]pyridin-8-ol--hydrogen chloride (1/1)
反応式
C([O:8][C:9]1[C:10]2[N:11]([CH:15]=[CH:16][N:17]=2)[CH:12]=[CH:13][CH:14]=1)C1C=CC=CC=1.[ClH:18]>>[ClH:18].[OH:8][C:9]1[C:10]2[N:11]([CH:15]=[CH:16][N:17]=2)[CH:12]=[CH:13][CH:14]=1参加物
3
実験手順
In 80 ml of concentrated hydrochloric acid is dissolved 5 g of 8-benzyloxyimidazo[1,2-a]pyridine, and the solution is stirred at room temperature for 24 hours and then concentrated. After addition of 1-butanol, water is azeotropically removed by distillation, and the residue is crystallized from diethyl ether to give 3.8 g of the above-identified compound.
後処理
- concentrationconcentrated
- additionAfter addition of 1-butanol, water
- customis azeotropically removed by distillation
- customthe residue is crystallized from diethyl ether
出典と根拠
- ORDレコード
- ord-039000c167554c4d9382c30686196a3f
- 出典データセット
- uspto-grants-1988_11
- 特許番号
- US04788185
反応ノート
読み込み中…