2-(Trifluoromethyl)benzoyl chloride → HCID 21283749、化合物

反応式

[Cl:1][C:2]1[C:3]([F:13])=[C:4]([CH:10]=[CH:11][CH:12]=1)[C:5](=[NH:9])[O:6][CH2:7][CH3:8].[F:14][C:15]([F:26])([F:25])[C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18](Cl)=[O:19]>>[F:14][C:15]([F:25])([F:26])[C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18]([N:9]=[C:5]([O:6][CH2:7][CH3:8])[C:4]1[CH:10]=[CH:11][CH:12]=[C:2]([Cl:1])[C:3]=1[F:13])=[O:19]

参加物

反応物 2

HCID 675612-(Trifluoromethyl)benzoyl chloride

HCID 21283785HCID 21283785、化合物

生成物 1

HCID 21283749HCID 21283749、化合物

実験手順

starting from ethyl 3-chloro-2-fluorobenzimidate and o-trifluoromethyl-benzoyl chloride there is obtained ethyl N-(o-trifluoromethyl-benzoyl)-2-fluoro-3-chlorobenzimidate and therefrom with methylhydrazine there is obtained 3-(3-chloro-2-fluorophenyl)-1-methyl-5-(o-trifluoromethyl-phenyl)-1H-1,2,4-triazole, m.p. 137°-140° C.;

出典と根拠

ORDレコード: ord-34aecfe84ef0405c864525ffcc7e8033
出典データセット: uspto-grants-1988_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04788210

反応ノート

読み込み中…