化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl 2-(3-methoxyphenyl)-4-quinazolinepropionate → N,N-diethyl-2-(3-methoxyphenyl)-4-quinazolinepropanamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl 2-(3-methoxyphenyl)-4-quinazolinepropionate | HCID 13769245 | — |
| 溶媒 | Diethylamine | HCID 8021 | — |
| 生成物 | N,N-diethyl-2-(3-methoxyphenyl)-4-quinazolinepropanamide | HCID 13769156 | 55.5% |
反応手順
The procedure is as in Example 1, starting with ethyl 2-(3-methoxyphenyl)-4-quinazolinepropionate (1.2 g) and diethylamine (30 cc). After chromatography on silica gel with a cyclohexane/ethyl acetate (1:1 by volume) mixture as eluant, and crystallization in isopropyl ether, N,N-diethyl-2-(3-methoxyphenyl)-4-quinazolinepropanamide (0.36 g), m.p. 87° C., is obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04788204 |
| 出典データセット | uspto-grants-1988_11 |
| ORD ID | ord-899babe8936a487ba126e7d4fda9b679 |
| 出典メモ | uspto-grants-1988_11 |