化工社化工社 化学情報印刷レポート · 研究参考用
Santonox → 2-(5-Phenyl-1-hydroxypentyl)-2-oxiranecarboxylic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Santonox | HCID 7308 | — |
| 反応物 | m-Chloroperbenzoic acid | HCID 70297 | — |
| 反応物 | beta-Hydroxy-alpha-methylenebenzeneheptanoic acid methyl ester | HCID 14348901 | — |
| 溶媒 | 1,2-Dichloroethane | HCID 11 | — |
| 生成物 | 2-(5-Phenyl-1-hydroxypentyl)-2-oxiranecarboxylic acid methyl ester | HCID 14348902 | — |
反応手順
A solution of 11.2 g (45 mmol) of β-hydroxy-α-methylenebenzeneheptanoic acid methyl ester in 300 ml of 1,2-dichloroethane is treated with 200 mg of 4,4'-thiobis(6-t-butyl-m-cresol) and 24.5 g (138 mmol) of m-chloroperoxybenzoic acid. The mixture is heated to reflux under nitrogen for 26 hours.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04788304 |
| 出典データセット | uspto-grants-1988_11 |
| ORD ID | ord-2dd5530f6dde4afbad48bab534e5a5a3 |
| 出典メモ | uspto-grants-1988_11 |