4-Nitrobenzoyl chloride → Methanone, (4-nitrophenyl)phenyl-

HRID 223288ノート

反応式

HRID 223288 の反応式
[N+:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8](Cl)=[O:9])=[CH:6][CH:5]=1)([O-:3])=[O:2].[Cl-].[Al+3].[Cl-].[Cl-]>C1C=CC=CC=1>[N+:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8](=[O:9])[C:4]2[CH:12]=[CH:11][CH:7]=[CH:6][CH:5]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2]

参加物

4

反応物 2

HCID 85024-Nitrobenzoyl chlorideHCID 6451240Aluminum(III) Chloride

生成物 1

HCID 70839Methanone, (4-nitrophenyl)phenyl-収率 182.4%

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

A total of 55.7 grams of p-nitrobenzoyl chloride was dissolved in 225 milliliters of benzene and, while stirring, 65 grams of anhydrous aluminum chloride was added thereto over a period of 40 minutes, all of which was done under a nitrogen atmosphere. After addition was completed, the mixture was stirred for 30 minutes on a steam bath and then poured over ice. Extraction of the resulting product with methylene chloride, followed by washing the organic layer with water, drying with anhydrous magnesium sulfate and filtering, resulted in the recovery of 62.2 grams of p-nitrobenzophenone.

後処理

  1. additionAfter addition
  2. stirringthe mixture was stirred for 30 minutes on a steam bath
  3. additionpoured over ice
  4. extractionExtraction of the resulting product with methylene chloride
  5. washby washing the organic layer with water
  6. dry with materialdrying with anhydrous magnesium sulfate
  7. filtrationfiltering

出典と根拠

ORDレコード
ord-3fb64bd2a90f493bbd3ed8da84044d07
出典データセット
uspto-grants-1982_10
特許番号
US04352942

反応ノート

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