2-Bromopropane → 1-(3-Chloro-5-trifluoromethyl-phenyl)-4-isopropyl-piperazine

HRID 2232896ノート

反応式

HRID 2232896 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]([N:12]2[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.[CH:18](Br)([CH3:20])[CH3:19]>>[Cl:1][C:2]1[CH:3]=[C:4]([N:12]2[CH2:17][CH2:16][N:15]([CH:18]([CH3:20])[CH3:19])[CH2:14][CH2:13]2)[CH:5]=[C:6]([C:8]([F:10])([F:11])[F:9])[CH:7]=1

参加物

3

反応物 2

HCID 63582-BromopropaneHCID 223451951-(3-Chloro-5-(trifluoromethyl)phenyl)piperazine

生成物 1

HCID 223451511-(3-Chloro-5-trifluoromethyl-phenyl)-4-isopropyl-piperazine

実験手順

Beginning with 1-(3-Chloro-5-trifluoromethyl-phenyl)-piperazine and iso-propylbromide, the title compound was recovered by the procedure described in Example 2. MS m/z (rel. intensity, 70 eV) 306 (M+, 30), 291 (bp), 206 (25), 193 (15), 179 (20).

後処理

  1. customthe title compound was recovered by the procedure

出典と根拠

ORDレコード
ord-024eb21157e94e0d9e31b24566cc0500
出典データセット
uspto-grants-2010_05
特許番号
USRE041315E1

反応ノート

読み込み中…