3-Aminopropionitrile → 2-(1,3-Benzothiazol-2-yl)ethan-1-amine
反応式
[NH2:1][CH2:2][CH2:3][C:4]#[N:5].N[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[SH:13]>CCO>[S:13]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[N:5]=[C:4]1[CH2:3][CH2:2][NH2:1]参加物
4
実験手順
A solution of 50 mg of 3-aminopropionitrile and 596 mg of 2-aminothiophenol in EtOH (15 mL) was heated at reflux for six h. After cooling the solution to room temperature, the reaction was concentrated and the residue was purified by silica gel chromatography to afford the title compound as a red oil. MS (M+H)+=179.1.
後処理
- temperatureat reflux for six h
- concentrationthe reaction was concentrated
- customthe residue was purified by silica gel chromatography
出典と根拠
- ORDレコード
- ord-1fd12dcc2a8149c4a2a880aee1a32940
- 出典データセット
- uspto-grants-2010_05
- 特許番号
- US07709473B2
反応ノート
読み込み中…