Hydrochloric Acid → HCID 59296015、化合物

反応式

Cl[S:2]([C:5]1[CH:14]=[C:13]2[C:8]([C:9]([C:16]([OH:18])=[O:17])=[CH:10][NH:11][C:12]2=[O:15])=[CH:7][CH:6]=1)(=[O:4])=[O:3].[CH3:19][NH:20][CH3:21].Cl>>[CH3:19][N:20]([CH3:21])[S:2]([C:5]1[CH:14]=[C:13]2[C:8]([C:9]([C:16]([OH:18])=[O:17])=[CH:10][NH:11][C:12]2=[O:15])=[CH:7][CH:6]=1)(=[O:4])=[O:3]

参加物

反応物 3

HCID 313Hydrochloric Acid

HCID 674Dimethylamine

HCID 59295966HCID 59295966、化合物

生成物 1

HCID 59296015HCID 59296015、化合物

実験手順

7-(Chlorosulfonyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid (0.8 g) was added to dimethylamine (15 ml) and the mixture was stirred for 18 h. The mixture was acidified with concentrated hydrochloric acid and then filtered to yield 7-[(dimethylamino)sulfonyl]-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid as a white solid.