HCID 68579940、化合物 → Methyl 2-chloro-6-(4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)isonicotinate
反応式
[Cl:1][C:2]1[C:6]([Cl:7])=[C:5]([CH3:8])[NH:4][C:3]=1[C:9](NC1CCN(C2SC=CN=2)CC1)=[O:10].Cl.[NH2:24][CH:25]1[CH2:30][CH2:29][N:28]([C:31]2[CH:32]=[C:33]([CH:38]=[C:39]([Cl:41])[N:40]=2)[C:34]([O:36][CH3:37])=[O:35])[CH2:27][CH2:26]1>>[Cl:41][C:39]1[CH:38]=[C:33]([CH:32]=[C:31]([N:28]2[CH2:27][CH2:26][CH:25]([NH:24][C:9]([C:3]3[NH:4][C:5]([CH3:8])=[C:6]([Cl:7])[C:2]=3[Cl:1])=[O:10])[CH2:30][CH2:29]2)[N:40]=1)[C:34]([O:36][CH3:37])=[O:35]参加物
3
実験手順
The title compound was prepared in a manner analogous to Example 18 starting from 3,4-dichloro-5-methyl-1H-pyrrole-2-carboxylic acid (Intermediate 3) and methyl 2-(4-aminopiperidin-1-yl)-6-chloroisonicotinate hydrochloride salt (Intermediate 93).
出典と根拠
- ORDレコード
- ord-504fe7ad21194b0ba9d7fe725257368e
- 出典データセット