4,5-Dibromo-2-nitroaniline → 4,5-Dibromobenzene-1,2-diamine

HRID 223450ノート

反応式

HRID 223450 の反応式
[Br:1][C:2]1[CH:3]=[C:4]([C:6]([N+:10]([O-])=O)=[CH:7][C:8]=1[Br:9])[NH2:5].[H][H]>[Ni].C(O)C>[Br:1][C:2]1[C:8]([Br:9])=[CH:7][C:6]([NH2:10])=[C:4]([NH2:5])[CH:3]=1

参加物

5

反応物 2

HCID 127110274,5-Dibromo-2-nitroanilineHCID 178418361HCID 178418361、化合物2 回

生成物 1

HCID 121969444,5-Dibromobenzene-1,2-diamine

試薬・触媒・溶媒 2

HCID 935Nickel触媒HCID 702Ethanol溶媒

実験手順

Five grams of 3,4-dibromo-6-nitroaniline were suspended in 200 ml. of anhydrous ethanol to which was added about 10 g. of Raney nickel. The hydrogenation mixture was placed in a low pressure hydrogenation apparatus at a hydrogen pressure of 55 psi. A rapid uptake of hydrogen occurred which ceased after about 25 minutes, at which time the deep yellow color originally present had been discharged indicating complete reduction of the nitro group to an amino group. The hydrogenation was continued for another half hour and the hydrogenation mixture was then worked up by filtering off the catalyst, washing the filtered catalyst, and stripping the volatile constituents from the filtrate. A yield of 4.1 g. of 4,5-dibromo-o-phenylenediamine was obtained.

後処理

  1. waitThe hydrogenation was continued for another half hour
  2. filtrationby filtering off the catalyst
  3. washwashing the filtered catalyst

出典と根拠

ORDレコード
ord-4a37a6c9df3a42889c4b7fcddb126bcc
出典データセット
uspto-grants-1982_10
特許番号
US04355030

反応ノート

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