1-[3-(tert-Butyldimethylsilyloxymethyl)phenyl]-3-mesitylthiourea → 1-(3-Hydroxymethylphenyl)-3-mesitylthiourea
反応式
[Si]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([NH:16][C:17]([NH:19][C:20]2[C:25]([CH3:26])=[CH:24][C:23]([CH3:27])=[CH:22][C:21]=2[CH3:28])=[S:18])[CH:13]=[CH:14][CH:15]=1)(C(C)(C)C)(C)C>C(O)C.Cl.O>[OH:8][CH2:9][C:10]1[CH:11]=[C:12]([NH:16][C:17]([NH:19][C:20]2[C:25]([CH3:26])=[CH:24][C:23]([CH3:27])=[CH:22][C:21]=2[CH3:28])=[S:18])[CH:13]=[CH:14][CH:15]=1参加物
5
実験手順
To 0.56 g (0.1.4 mmol) of 1-[3-(tert-butyldimethylsilyloxymethyl)phenyl]-3-mesitylthiourea in 10 mL of ethanol was added 10 drops of concentrated hydrochloric acid. After 30 min, the reaction was diluted with water and the precipitate that formed was collected to give 0.35 g (86%) of the title compound as a white powder.