6-(Morpholino)pyridin-3-amine → HCID 59301450、化合物

反応式

[CH:1]([C:4]1[O:8][C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[N:6][C:5]=1[C:15]([OH:17])=O)([CH3:3])[CH3:2].[N:18]1([C:24]2[N:29]=[CH:28][C:27]([NH2:30])=[CH:26][CH:25]=2)[CH2:23][CH2:22][O:21][CH2:20][CH2:19]1>>[N:18]1([C:24]2[N:29]=[CH:28][C:27]([NH:30][C:15]([C:5]3[N:6]=[C:7]([C:9]4[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=4)[O:8][C:4]=3[CH:1]([CH3:2])[CH3:3])=[O:17])=[CH:26][CH:25]=2)[CH2:23][CH2:22][O:21][CH2:20][CH2:19]1

参加物

反応物 2

HCID 1040596-(Morpholino)pyridin-3-amine

HCID 201167172-Phenyl-5-(propan-2-yl)-1,3-oxazole-4-carboxylic acid

生成物 1

HCID 59301450HCID 59301450、化合物

実験手順

With a procedure similar to example 16 above, 5-isopropyl-2-phenyl-oxazole-4-carboxylic acid (6-morpholin-4-yl-pyridin-3-yl)-amide was prepared from 5-isopropyl-2-phenyl-oxazole-4-carboxylic acid and 6-morpholin-4-yl-pyridin-3-ylamine. LCMS calcd for C22H24N4O3 (m/e) 392, obsd 393 (M+H).

出典と根拠

ORDレコード: ord-1f9d281f8c3e402aa77deea2cea86e70
出典データセット: uspto-grants-2010_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07714126B2

反応ノート

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