3-Ethylpent-1-yn-3-amine → N-(1,1-diethyl-2-propynyl)-3,5-difluoro-4-(2-propynyloxy)benzamide

HRID 2236358

反応式

HRID 2236358 の反応式
[CH2:1]([C:3]([NH2:8])([CH2:6][CH3:7])[C:4]#[CH:5])[CH3:2].[F:9][C:10]1[CH:11]=[C:12]([CH:16]=[C:17]([F:23])[C:18]=1[O:19][CH2:20][C:21]#[CH:22])[C:13](Cl)=[O:14]>>[CH2:4]([C:3]([NH:8][C:13](=[O:14])[C:12]1[CH:16]=[C:17]([F:23])[C:18]([O:19][CH2:20][C:21]#[CH:22])=[C:10]([F:9])[CH:11]=1)([CH2:6][CH3:7])[C:1]#[CH:2])[CH3:5]

参加物

3

反応物 2

HCID 767103-Ethylpent-1-yn-3-amineHCID 574456963,5-Difluoro-4-(2-propynyloxy)benzoyl chloride

生成物 1

HCID 59301827N-(1,1-diethyl-2-propynyl)-3,5-difluoro-4-(2-propynyloxy)benzamide

実験手順

According to the same method as that of Production Example 1, 1,1-diethyl-2-propynylamine was used in place of 2,2-dimethylpropylamine, 3,5-difluoro-4-(2-propynyloxy)benzoyl chloride was used in place of 4-(2-propynyloxy)-3-methoxybenzoyl chloride to obtain N-(1,1-diethyl-2-propynyl)-3,5-difluoro-4-(2-propynyloxy)benzamide (hereinafter, described as the compound 52 of the present invention) represented by the formula:

出典と根拠

ORDレコード
ord-ed91547e90744c1289436e74d2df417a
出典データセット
uspto-grants-2010_05
特許番号
US07714168B2

関連ノート

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