Hydrazine → 4-Aminocatechol
反応式
[N+:1]([C:4]1[CH:5]=[C:6]([OH:11])[C:7](=[CH:9][CH:10]=1)[OH:8])([O-])=O.NN>CO.[Ni]>[OH:11][C:6]1[CH:5]=[C:4]([CH:10]=[CH:9][C:7]=1[OH:8])[NH2:1]参加物
5
実験手順
To a solution of 4-nitrocatechol (310 mg, 2.0 mmol) in methanol (20 mL) is added hydrazine (200 μL) and a catalytic amount of Raney-Nickel (50 mg). The reaction mixture is left to stir at ambient temperature for 16 hours. The solution is then filtered over celite to remove Raney-Nickel and the filtrate evaporated to dryness. The 3,4-dihydroxyaniline thus produced is used as such for the next reaction.
後処理
- waitThe reaction mixture is left
- filtrationThe solution is then filtered over celite
- customto remove Raney-Nickel
- customthe filtrate evaporated to dryness
出典と根拠
- ORDレコード
- ord-5a662f435afc4a73b3b9d115fa8645d3
- 出典データセット
- uspto-grants-2010_05
- 特許番号
- US07713994B2
反応ノート
読み込み中…