反応式
FC1C=CC(CN[C:10](=[O:18])[C@@H:11]2[CH2:15][CH2:14][C:13](=[O:16])[N:12]2[CH3:17])=C(C(F)(F)F)C=1.[Cl:23][C:24]1[CH:29]=[C:28]([Cl:30])[CH:27]=[CH:26][C:25]=1[CH2:31][NH2:32].FC1C=CC(CN)=C(C(F)(F)F)C=1>>[Cl:23][C:24]1[CH:29]=[C:28]([Cl:30])[CH:27]=[CH:26][C:25]=1[CH2:31][NH:32][C:10](=[O:18])[C@@H:11]1[CH2:15][CH2:14][C:13](=[O:16])[N:12]1[CH3:17]参加物
4
実験手順
N-[(2,4-dichlorophenyl)methyl]-1-methyl-5-oxoprolinamide was prepared in a manner analogous to that described above for the synthesis of N-{[4-fluoro-2-(trifluoromethyl)phenyl]methyl}-1-methyl-5-oxoprolinamide (Example 83) but [(2,4-dichlorophenyl)methyl]amine was substituted for {[4-fluoro-2-(trifluoromethyl)phenyl]methyl}amine.
出典と根拠
- ORDレコード
- ord-96d87ec1adb441a6ac59ef8398b3b279
- 出典データセット
- uspto-grants-2010_05
- 特許番号
- US07718693B2
関連ノート
読み込み中…