3-[(4-chlorophenyl)thio]-2,5-dimethyl-1H-indole → 4-Chloro-3-(4-chlorobenzene-1-sulfonyl)-2-methyl-1H-indole
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([C:11]2[C:19]3[C:14](=[CH:15][CH:16]=[C:17](C)[CH:18]=3)[NH:13][C:12]=2[CH3:21])(=[O:10])=[O:9])=[CH:4][CH:3]=1.[Cl:22]C1C=CC(SC2C3C(=CC=C(C)C=3)NC=2C)=CC=1>>[Cl:22][C:18]1[CH:17]=[CH:16][CH:15]=[C:14]2[C:19]=1[C:11]([S:8]([C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=1)(=[O:10])=[O:9])=[C:12]([CH3:21])[NH:13]2参加物
3
実験手順
The subtitle compound was prepared by the method of example 1 part (b) using the product from part (a). Product was purified using Flash column chromatography (33% EtOAc/hexane as eluent).
後処理
- customProduct was purified
出典と根拠
- ORDレコード
- ord-70eff9d96ca54405876dba88f0f7a618
- 出典データセット
- uspto-grants-2010_05
- 特許番号
- US07723373B2
反応ノート
読み込み中…