Iodine → HCID 68479364、化合物

反応式

[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH2:11][C:12]([OH:14])=[O:13])[C:6]([CH3:15])=[CH:5]2.II.[F:18][C:19]([F:28])([F:27])[C:20]1[CH:25]=[CH:24][C:23]([SH:26])=[CH:22][CH:21]=1>>[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH2:11][C:12]([OH:14])=[O:13])[C:6]([CH3:15])=[C:5]2[S:26][C:23]1[CH:22]=[CH:21][C:20]([C:19]([F:18])([F:27])[F:28])=[CH:25][CH:24]=1

参加物

反応物 3

HCID 807Iodine

HCID 1366534-(Trifluoromethyl)thiophenol

HCID 674666192(5-fluoro-2-methyl-1H-indol-1-yl)acetic acid

生成物 1

HCID 68479364HCID 68479364、化合物

実験手順

Prepared by the method of example 26 step c) using the product of example 26 step b) (0.55 g), iodine (0.98 g) and 4-trifluoromethylbenzenethiol (0.67 g) to give the subtitle compound as a solid (0.25 g).

後処理

customPrepared by the method of example 26 step c)

出典と根拠

ORDレコード: ord-a51a91ddc88a4d7db2afe39ac0ce1525
出典データセット: uspto-grants-2010_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07723373B2

反応ノート

読み込み中…