Dimethylamine → HCID 11326074、化合物
反応式
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]([CH2:15][C:16]([F:19])([F:18])[F:17])[C@H:10]([C:12]([OH:14])=O)[CH3:11])=[CH:5][C:4]=1[C:20]([F:23])([F:22])[F:21])#[N:2].[CH3:24][NH:25][CH3:26]>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]([CH2:15][C:16]([F:18])([F:19])[F:17])[C@H:10]([C:12]([N:25]([CH3:26])[CH3:24])=[O:14])[CH3:11])=[CH:5][C:4]=1[C:20]([F:22])([F:21])[F:23])#[N:2]参加物
3
実験手順
Synthesized as described in example 3 using N-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2,2,2-trifluoroethyl)alanine and dimethylamine: 1H NMR (400 MHz, CDCl3) δ 7.69 (d, J=8.8 Hz, 1H), 7.10 (d, J=2.7 Hz, 1H), 7.01 (dd, J=9.0, 2.7 Hz, 1H), 4.80 (q, J=7.0 Hz, 1H), 4.30 (m, 2H), 3.07 (s, 3H), 2.96 (s, 3H), 1.48 (d, J=7.0 Hz, 3H).
後処理
- customSynthesized
出典と根拠
- ORDレコード
- ord-dd5b0e0d51884f02a9e09ebef470ee67
- 出典データセット
- uspto-grants-2010_05
- DOI