化工社化工社 化学情報印刷レポート · 研究参考用
2-Fluoro-5-iodotoluene → 4-(4-Difluoromethoxy-phenylethynyl)-1-fluoro-2-methyl-benzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Fluoro-5-iodotoluene | HCID 521178 | — |
| 反応物 | 1-(Difluoromethoxy)-4-ethynylbenzene | HCID 2778497 | — |
| 生成物 | 4-(4-Difluoromethoxy-phenylethynyl)-1-fluoro-2-methyl-benzene | HCID 59305311 | — |
反応手順
The title compound was prepared in substantially the same manner as described in Example 12, step 3 starting from 1-Fluoro-4-iodo-2-methyl-benzene (0.125 g, 0.53 mmol), and 1-Difluoromethoxy-4-ethynyl-benzene (0.09 g, 0.53 mmol), and was obtained as a yellow semi solid, (0.141 g, 96%), and identified by NMR and mass spectral analyses. MS (EI+): 276 (M+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07723368B2 |
| 出典データセット | uspto-grants-2010_05 |
| ORD ID | ord-b5849fc4cf3a417f8b6172df3497d72b |
| 出典メモ | uspto-grants-2010_05 |