Cyclohexanone → N-cyclohexylidene(3-phenoxybenzylamine)

反応式

[O:1]([C:8]1[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=1)[CH2:11][NH2:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:16]1(=O)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1>>[C:16]1(=[N:12][CH2:11][C:10]2[CH:13]=[CH:14][CH:15]=[C:8]([O:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)[CH:9]=2)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1

参加物

反応物 2

HCID 7967Cyclohexanone

HCID 10948363-Phenoxy-benzylamine

生成物 1

HCID 23332475N-cyclohexylidene(3-phenoxybenzylamine)収率 58.8%

実験手順

The procedure is carried out as described in Example 1(b) but with the use of 50 g (0.25 mol) of 3-phenoxybenzylamine and 25 g (0.255 mol) of cyclohexanone. Distillation leaves 41 g (0.147 mol) of N-cyclohexylidene(3-phenoxybenzylamine), corresponding to a yield of 58.7% of theory; b.p. 135°-136° C./4 Pa.

後処理

distillationDistillation

出典と根拠

ORDレコード: ord-8c9b2432a9be468692207c8de8a277d2
出典データセット: uspto-grants-1980_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04231962

反応ノート

読み込み中…