3-Aminobenzonitrile → HCID 16718203、化合物
反応式
[N+:1](=[C:3]1[C:8](=[O:9])[CH2:7][CH2:6][CH2:5][C:4]1=[O:10])=[N-].[C:11]([C:13]1[CH:14]=[C:15]([CH:17]=[CH:18][CH:19]=1)N)#[N:12]>C1C=CC=CC=1.C([O-])(=O)C.[Rh+3].C([O-])(=O)C.C([O-])(=O)C>[OH:10][C:4]1[CH2:5][CH2:6][CH2:7][C:8](=[O:9])[C:3]=1[N:1]([C:3]1[C:8](=[O:9])[CH2:7][CH2:6][CH2:5][C:4]=1[OH:10])[C:18]1[CH:19]=[C:13]([CH:14]=[CH:15][CH:17]=1)[C:11]#[N:12]参加物
5
反応条件
- 温度
- 80 °C
実験手順
2-Diazo-cyclohexane-1,3-dione (2 mmoL), prepared by the literature known procedure, 3-cyano-aniline (1 mmoL) and rhodium acetate dimmer (0.01 mmoL) in benzene (10 mL) were heated at 80° C. for 4˜6 hrs. The solid was filtered off and the filtrate was concentrated to give a yellow oil, which was purified by silica gel chromatography to afford the title compound as a white solid.