Cyclohexanecarboxaldehyde → HCID 68548829、化合物
反応式
[CH:1]1([CH:7]=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:9][O:10][C:11]([C:13]1[S:25][C:16]2[C:17]3[CH:18]=[CH:19][CH:20]=[C:21]([NH2:24])[C:22]=3[S:23][C:15]=2[C:14]=1[O:26][CH2:27][C:28]([O:30][CH2:31][CH3:32])=[O:29])=[O:12]>>[CH3:9][O:10][C:11]([C:13]1[S:25][C:16]2[C:17]3[CH:18]=[CH:19][CH:20]=[C:21]([NH:24][CH2:7][CH:1]4[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]4)[C:22]=3[S:23][C:15]=2[C:14]=1[O:26][CH2:27][C:28]([O:30][CH2:31][CH3:32])=[O:29])=[O:12]参加物
3
実験手順
Step A Reductive Amination: Addition of cyclohexane carboxaldehyde (0.063 mL, 0.61 mmol), to 7-Amino-1-ethoxycarbonylmethoxy-3,8-dithia-cyclopenta[a]indene-2-carboxylic acid methyl ester (250 mg, 0.61 mmol) was carried out following a procedure similar to that delineated in step A (“reductive amination,” Example 25) affording 180 mg of 7-(Cyclohexylmethyl-amino)-1-ethoxycarbonylmethoxy-3,8-dithia-cyclopenta[a]indene-2-carboxylic acid methyl ester as a viscous yellow oil.
出典と根拠
- ORDレコード
- ord-588c79519a2d4e9eaef10090c7d9cb18
- 出典データセット
- uspto-grants-2010_03