Peracetic Acid → HCID 178476552、化合物

反応式

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([I:8])[CH:3]=1.[C:9]([O:12]O)(=[O:11])[CH3:10]>>[C:9]([O-:12])(=[O:11])[CH3:10].[C:9]([O-:12])(=[O:11])[CH3:10].[Cl:1][C:2]1[CH:3]=[C:4]([I+2:8])[CH:5]=[CH:6][CH:7]=1

参加物

反応物 2

HCID 6585Peracetic Acid

HCID 122691-Chloro-3-iodobenzene

生成物 1

HCID 178476552HCID 178476552、化合物収率 367.3%

実験手順

1-Chloro-3-iodobenzene (5.0 g, 21 mmol) was stirred at 30° C. Peracetic acid (40%, 8.35 mL, 50.3 mmol) was added drop wise to the solution and the reaction was allowed to stir for 12 h. The white solid that formed was filtered, washed 1 time with 10% acetic acid, and 3 times with hexanes and dried in vacuo to afford the title product (27.5 g, 92%) as a white solid.

後処理

customThe white solid that formed
filtrationwas filtered
washwashed 1 time with 10% acetic acid, and 3 times with hexanes
customdried in vacuo

出典と根拠

ORDレコード: ord-aad17f4f3c484a71a796ac7bc42839f5
出典データセット: uspto-grants-2010_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07678796B2

反応ノート

読み込み中…

参加物