4-(Trifluoromethyl)benzoic acid → Ethyl 3-oxo-3-(4-(trifluoromethyl)phenyl)propanoate

HRID 2244136

反応式

HRID 2244136 の反応式
O=C(C1SC=CC=1)CC(OCC)=O.S1C=CC=C1C1C=CN=C(N)N=1.C[C:27]1([CH3:35])[O:32][C:31](=[O:33])[CH2:30][C:29](=[O:34])O1.[F:36][C:37]([F:48])([F:47])[C:38]1[CH:46]=[CH:45][C:41](C(O)=O)=[CH:40][CH:39]=1>>[O:34]=[C:29]([C:41]1[CH:45]=[CH:46][C:38]([C:37]([F:48])([F:47])[F:36])=[CH:39][CH:40]=1)[CH2:30][C:31]([O:32][CH2:27][CH3:35])=[O:33]

参加物

5

反応物 4

HCID 99664-(Trifluoromethyl)benzoic acidHCID 162492,2-Dimethyl-1,3-dioxane-4,6-dioneHCID 255159Ethyl 3-oxo-3-(thiophen-2-yl)propanoateHCID 27644074-(Thiophen-2-yl)pyrimidin-2-amine

生成物 1

HCID 2760281Ethyl 3-oxo-3-(4-(trifluoromethyl)phenyl)propanoate

実験手順

This material is prepared by a method analogous to that described for preparation of ethyl 3-oxo-3-(2-thienyl)propanoate in preparation of 1D, starting from 2,2-dimethyl-1,3-dioxane-4,6-dione and 4-(trifluoromethyl)benzoic acid.

後処理

  1. customThis material is prepared by a method analogous to

出典と根拠

ORDレコード
ord-ffe3ea363c1f4950a75ef69e62fac22c
出典データセット
uspto-grants-2010_03
特許番号
US07678804B2

関連ノート

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