化工社化工社 化学情報印刷レポート · 研究参考用
2,6-Dimethoxybenzoic Acid → 3-Bromo-2,6-dimethoxybenzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,6-Dimethoxybenzoic Acid | HCID 15109 | — |
| 反応物 | Bromine | HCID 24408 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | 3-Bromo-2,6-dimethoxybenzoic acid | HCID 2774744 | — |
反応手順
A solution of 15 ml of bromine (0.3 mol) in 50 ml of chloroform is added dropwise while stirring and cooling in ice to 54.9 g (0.3 mol) of 2,6-dimethoxybenzoic acid in 150 ml of dioxan. The solution is left at room temperature overnight. The solvent is evaporated and the residue recrystallized from aqueous ethanol. Yield: 59.3 g, m.p. 144°-45° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04232037 |
| 出典データセット | uspto-grants-1980_11 |
| ORD ID | ord-4a69d9981df04110bfcdd27b9a858423 |
| 出典メモ | uspto-grants-1980_11 |