Sulfuryl chloride → HCID 12878331、化合物

HRID 224428ノート

反応式

HRID 224428 の反応式
[CH3:1][O:2][C:3](=[O:19])[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]2[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]2)=[CH:7][C:6]=1[O:17][CH3:18].S(Cl)([Cl:23])(=O)=O>C(Cl)Cl>[CH3:1][O:2][C:3](=[O:19])[CH2:4][C:5]1[CH:10]=[C:9]([Cl:23])[C:8]([CH:11]2[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]2)=[CH:7][C:6]=1[O:17][CH3:18]

参加物

4

反応物 2

HCID 24648Sulfuryl chlorideHCID 12878330HCID 12878330、化合物

生成物 1

HCID 12878331HCID 12878331、化合物

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

The (4-cyclohexyl-2-methyoxyphenyl)-acetic acid methylester obtained as above is dissolved in 500 ml of methylene chloride, and 5.5 ml of sulphuryl chloride and 200 mg of silica gel are added. After stirring at 22° for 60 hours, there is substantial evaporation, and the residue is chromatographed on 300 g of silica gel. A homogeneous product is extracted with methylene chloride.

後処理

  1. customevaporation
  2. customthe residue is chromatographed on 300 g of silica gel
  3. extractionA homogeneous product is extracted with methylene chloride

出典と根拠

ORDレコード
ord-c229a8c5a05c409f85627446d25ffdc8
出典データセット
uspto-grants-1980_11
特許番号
US04232039

反応ノート

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