Palmitic Acid → 2-Methyl-5-hexadecanoylhydroquinone

HRID 224470

反応式

HRID 224470 の反応式
B(F)(F)F.[C:5]([OH:22])(=O)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].[CH3:23][C:24]1[CH:30]=[C:29]([OH:31])[CH:28]=[CH:27][C:25]=1[OH:26].C([O-])(=O)C.[Na+]>O.C(Cl)Cl>[CH3:23][C:24]1[CH:30]=[C:29]([OH:31])[C:28]([C:5](=[O:22])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])=[CH:27][C:25]=1[OH:26]

参加物

7

反応物 4

HCID 985Palmitic AcidHCID 6356Boron trifluorideHCID 7253MethylhydroquinoneHCID 517045Sodium Acetate

生成物 1

HCID 147165312-Methyl-5-hexadecanoylhydroquinone

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 6344Dichloromethane溶媒

実験手順

Boron trifluoride was introduced with vigorous refluxing until saturation into a mixture of 27.2 g of palmitic acid, 13.7 g of 2-methylhydroquinone and 45 ml of methylene chloride. After standing overnight the mixture was refluxed for another hour and then decomposed with stirring in a solution of 25 g of sodium acetate in 220 ml of water. After 45 min the solution in methylene chloride was separated and evaporated. The residue was stirred with methanol, filtered with suction and recrystallized from n-chlorobutane.

後処理

  1. temperaturethe mixture was refluxed for another hour
  2. customAfter 45 min the solution in methylene chloride was separated
  3. customevaporated
  4. filtrationfiltered with suction
  5. customrecrystallized from n-chlorobutane

出典と根拠

ORDレコード
ord-db9aa316efaf44f8a6f8972152474a09
出典データセット
uspto-grants-1980_11
特許番号
US04232107

関連ノート

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