2'-Dimethylaminomethylbiphenyl-4-ylamine → N-[4-(2-dimethylaminomethyl-phenyl)phenyl]-2-(2-methylphenyl)-2-(4-chlorophenylaminocarbonylamino)-acetamide

HRID 2244989

反応式

HRID 2244989 の反応式
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]([NH:12][C:13]([NH:15][C:16]1[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=1)=[O:14])[C:9]([OH:11])=O.[CH3:23][N:24]([CH2:26][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=1[C:33]1[CH:38]=[CH:37][C:36]([NH2:39])=[CH:35][CH:34]=1)[CH3:25]>>[CH3:25][N:24]([CH2:26][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=1[C:33]1[CH:34]=[CH:35][C:36]([NH:39][C:9](=[O:11])[CH:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[CH3:1])[NH:12][C:13]([NH:15][C:16]2[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=2)=[O:14])=[CH:37][CH:38]=1)[CH3:23]

参加物

3

反応物 2

HCID 588976922'-Dimethylaminomethylbiphenyl-4-ylamineHCID 68689841HCID 68689841、化合物

生成物 1

HCID 11497388N-[4-(2-dimethylaminomethyl-phenyl)phenyl]-2-(2-methylphenyl)-2-(4-chlorophenylaminocarbonylamino)-acetamide

実験手順

The titled compound was prepared analogously as describe in EXAMPLE 55, using 2-(2-methylphenyl)-2-(4-chlorophenylaminocarbonylamino)-acetic acid and 4-(2-dimethylaminomethyl-phenyl)phenylamine MS 527.7 and 529.6 (M+H, Cl pattern).

出典と根拠

ORDレコード
ord-bbbe7ca13d2249d898577db05f702484
出典データセット
uspto-grants-2010_03
特許番号
US07678913B2

関連ノート

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