Zincchloride → 3-pyridylmethyl N-(4-cyanophenyl)thiocarbamate zinc chloride

HRID 224571ノート

反応式

HRID 224571 の反応式
[Cl-:1].[Zn+2:2].[Cl-].[N:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH2:10][O:11][C:12](=[S:22])[NH:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]#[N:21])=[CH:16][CH:15]=2)[CH:5]=1>COCCO>[Cl-:1].[Zn+2:2].[C:20]([C:17]1[CH:18]=[CH:19][C:14]([NH:13][C:12](=[S:22])[O:11][CH2:10][C:6]2[CH:5]=[N:4][CH:9]=[CH:8][CH:7]=2)=[CH:15][CH:16]=1)#[N:21].[Cl-:1]

参加物

4

反応物 2

HCID 3007855Zincchloride2 回HCID 12790266O-[(Pyridin-3-yl)methyl] (4-cyanophenyl)carbamothioate

生成物 1

HCID 867365583-pyridylmethyl N-(4-cyanophenyl)thiocarbamate zinc chloride

試薬・触媒・溶媒 1

HCID 80192-Methoxyethanol溶媒2 回

実験手順

The zinc chloride metal salt complex of Example I is made by dissolving 3-pyridylmethyl-N-(4-cyanophenyl)thiocarbamate (2.69 g., 0.01 mole) in 75 ml. of methyl cellosolve and adding to this stirred solution; a solution of zinc chloride (0.68 g., 0.005 mole) in 10 ml. of methyl cellosolve. The resulting solution is stirred at room temperature for 18 hours. The solvent is removed in vacuo and the residue is slurried in 30 ml. of methanol and collected on a filter to give 2.5 g. melting at 174°-5° C. with decomposition.

後処理

  1. customThe solvent is removed in vacuo
  2. customof methanol and collected on
  3. filtrationa filter
  4. customto give 2.5 g

出典と根拠

ORDレコード
ord-9f2b28fa0cdf4290bfb269046261837d
出典データセット
uspto-grants-1980_11
特許番号
US04233289

反応ノート

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