Hydroxylamine → 2-Fluoro-N'-hydroxy-4-(methanesulfonyl)benzene-1-carboximidamide
反応式
[F:1][C:2]1[CH:9]=[C:8]([S:10]([CH3:13])(=[O:12])=[O:11])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[NH2:14][OH:15]>C(O)C>[F:1][C:2]1[CH:9]=[C:8]([S:10]([CH3:13])(=[O:12])=[O:11])[CH:7]=[CH:6][C:3]=1[C:4](=[N:14][OH:15])[NH2:5]参加物
4
反応条件
- 温度
- 90 °C
実験手順
To a stirred solution of the product from Step E (0.29 g, 0.144 mmol) in ethanol (15 mL) was added hydroxylamine (50% in water, 3.0 mL). The reaction was heated at 90° C. for 3 h. The reaction was then concentrated to give the desired product.
後処理
- concentrationThe reaction was then concentrated
出典と根拠
- ORDレコード
- ord-c72f38cdac23496b9ee55ba9e6cbc827
- 出典データセット
- uspto-grants-2010_03
- 特許番号
- US07687492B2
反応ノート
読み込み中…