1-Methyl-3-aminopyrazole → HCID 23160299、化合物

HRID 2246329ノート

反応式

HRID 2246329 の反応式
Cl[C:2]1[C:7]([CH:8]([F:10])[F:9])=[CH:6][CH:5]=[CH:4][N:3]=1.[NH2:11][C:12]1[CH:16]=[CH:15][N:14]([CH3:17])[N:13]=1.Cl[C:19]1[C:28]2[C:23](=[CH:24][CH:25]=[C:26]([OH:29])[CH:27]=2)[N:22]=[CH:21][N:20]=1>>[F:9][CH:8]([F:10])[C:7]1[C:2]([O:29][C:26]2[CH:27]=[C:28]3[C:23](=[CH:24][CH:25]=2)[N:22]=[CH:21][N:20]=[C:19]3[NH:11][C:12]2[CH:16]=[CH:15][N:14]([CH3:17])[N:13]=2)=[N:3][CH:4]=[CH:5][CH:6]=1

参加物

4

反応物 3

HCID 1372541-Methyl-3-aminopyrazoleHCID 231602734-Chloroquinazolin-6-olHCID 231603622-Chloro-3-(difluoromethyl)pyridine

生成物 1

HCID 23160299HCID 23160299、化合物

実験手順

The compound of Example 122 was manufactured by the same method as in Example 95, by a similar method thereto or by a combination of such a method with a conventional method using 2-chloro-3-(difluoromethyl)pyridine, 3-amino-1-methyl-1H-pyrazole and 4-chloro-6-hydroxy-quinazoline.

出典と根拠

ORDレコード
ord-b6199f44cf964b4393e0201b8a5e0342
出典データセット
uspto-grants-2010_03
特許番号
US07687502B2

反応ノート

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