HCID 11309757、化合物 → Methyl (1H-pyrrol-1-yl)acetate
反応式
[CH3:1][O:2][C:3](=[O:12])[CH2:4][N:5]([CH2:9][CH:10]=[CH2:11])[CH2:6]C=C>ClC1C=CC=CC=1>[N:5]1([CH2:4][C:3]([O:2][CH3:1])=[O:12])[CH:6]=[CH:11][CH:10]=[CH:9]1参加物
3
反応条件
- 温度
- 65 °C
実験手順
0.22 g (1.3 mmole) of the diallylglycine methyl ester prepared in example 27 was dissolved in 3 ml chlorobenzene after which 0.046 g (0,064 mmole) of the bimetallic ruthenium complex 3.e prepared in example 24 was added. The mixture was stirred for 16 hours at 65° C. The catalyst was removed after evaporation of chlorobenzene by column chromatography, providing with 100% selectivity 0.05 g (0.36 mmole, yield 28%) methyl 1H-pyrrole-1-ylacetate. This product was further characterised by the following spectra:
後処理
- additionwas added
- customThe catalyst was removed
- customafter evaporation of chlorobenzene by column chromatography
出典と根拠
- ORDレコード
- ord-b6461f9c819044c3843a60f213daa0f9
- 出典データセット
- uspto-grants-2010_03
- 特許番号
- US07687635B2
反応ノート
読み込み中…