Bromine → 1-Bromo-1-(3-methanesulphonyl-phenyl)-propanone

HRID 2247398ノート

反応式

HRID 2247398 の反応式
[CH3:1][S:2]([C:5]1[CH:6]=[C:7]([CH2:11][C:12](=[O:14])[CH3:13])[CH:8]=[CH:9][CH:10]=1)(=[O:4])=[O:3].[Br:15]Br>O1CCOCC1>[Br:15][CH:11]([C:7]1[CH:8]=[CH:9][CH:10]=[C:5]([S:2]([CH3:1])(=[O:3])=[O:4])[CH:6]=1)[C:12](=[O:14])[CH3:13]

参加物

4

反応物 2

HCID 24408BromineHCID 665884811-(3-(Methylsulfonyl)phenyl)propan-2-one

生成物 1

HCID 858616531-Bromo-1-(3-methanesulphonyl-phenyl)-propanone

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

A stirred solution of 1-(3-methanesulphonyl-phenyl)-propan-2-one (176b) (0.25 g, 1.18 mmol) in dioxane (10 ml) at 5° C. is treated with bromine (0.131 g, 0.82 mmol) added in two portions. The reaction is stirred and allowed to warm up to room temperature. The solvent is removed in vacuo to yield an orange oil of the titled compound.

後処理

  1. additionadded in two portions
  2. customThe solvent is removed in vacuo

出典と根拠

ORDレコード
ord-0a5f01175050466a8c1e5d5efcf254ae
出典データセット
uspto-grants-2010_03
特許番号
US07687637B2

反応ノート

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