Hydrogen Peroxide → HCID 178433055、化合物

HRID 224776

反応式

HRID 224776 の反応式
OO.[CH3:3][S:4][CH2:5][C:6]1[N:11]=[C:10]([OH:12])[C:9]([CH3:13])=[C:8]([CH3:14])[N:7]=1.CC[O:17]CC>C(O)(=O)C>[CH3:3][S:4]([CH2:5][C:6]1[N:11]=[C:10]([OH:12])[C:9]([CH3:13])=[C:8]([CH3:14])[N:7]=1)=[O:17]

参加物

5

反応物 3

HCID 784Hydrogen PeroxideHCID 3283Diethyl EtherHCID 178503663HCID 178503663、化合物

生成物 1

HCID 178433055HCID 178433055、化合物収率 85%

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

6.8 g (0.1 mol) of 50% strength hydrogen peroxide were added to a mixture of 18.4 g (0.1 mol) of 2-methylthiomethyl-4-hydroxy-5,6-dimethylpyrimidine in 100 ml of glacial acetic acid at 10° C. The mixture was subsequently stirred for 3 hours, without cooling, about 300 ml of ether were added and the product which had precipitated was filtered off. 17 g (85% of theory) of 2-methysulphinylmethyl-4-hydroxy-5,6-dimethylpyrimidine were thus obtained in the form of a grey powder with a melting point of 112° C. ##STR7##

後処理

  1. temperaturewithout cooling
  2. customthe product which had precipitated
  3. filtrationwas filtered off

出典と根拠

ORDレコード
ord-9e5355ceecc2404b9ab66c2cbd785817
出典データセット
uspto-grants-1980_11
特許番号
US04234587

関連ノート

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