Methylthiouracil → HCID 135559187、化合物

HRID 2247852ノート

反応式

HRID 2247852 の反応式
[Cl-].Cl[CH2:3][C:4]1[CH:9]=[CH:8][C:7]([CH2:10][CH3:11])=[CH:6][NH+:5]=1.[CH3:12][C:13]1[NH:20][C:18](=[S:19])[NH:17][C:15](=[O:16])[CH:14]=1>>[CH2:10]([C:7]1[CH:8]=[CH:9][C:4]([CH2:3][S:19][C:18]2[NH:17][C:15](=[O:16])[CH:14]=[C:13]([CH3:12])[N:20]=2)=[N:5][CH:6]=1)[CH3:11]

参加物

3

反応物 2

HCID 667493MethylthiouracilHCID 1981607471670-78-5

生成物 1

HCID 135559187HCID 135559187、化合物収率 51%

実験手順

The title compound is prepared from 2-chloromethyl-5-ethylpyridinium chloride (m.p.: 126°-128° C.) and 6-methyl-2-thiouracyl by using the process described in Example 12. After recrystallization from ethanol the title compound is obtained as a white crystalline product in a yield of 51%, m.p.: 127°-128° C.

後処理

  1. customAfter recrystallization from ethanol the title compound
  2. customis obtained as a white crystalline product in a yield of 51%, m.p.: 127°-128° C.

出典と根拠

ORDレコード
ord-7f9d900f3ea945f7acc0f0689b1dd4e1
出典データセット
uspto-grants-1991_08
特許番号
US05037830

反応ノート

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