Potassium Hydroxide → Methyl 3-hydroxy-5-mercapto-4-methylthiphene-2-carboxylate

HRID 2248746ノート

反応式

HRID 2248746 の反応式
C(SC1SC=CC=1)(=O)C.C([S:13][C:14]1[S:18][C:17]([C:19]([O:21][CH3:22])=[O:20])=[C:16]([OH:23])[C:15]=1[CH3:24])(=O)C.[OH-].[K+]>CO>[OH:23][C:16]1[C:15]([CH3:24])=[C:14]([SH:13])[S:18][C:17]=1[C:19]([O:21][CH3:22])=[O:20]

参加物

5

反応物 3

HCID 14797Potassium HydroxideHCID 13133366Thiophene-2-thiol, S-acetyl-HCID 54710754Methyl 5-acetylthio-3-hydroxy-4-methylthiophene-2-carboxylate

生成物 1

HCID 54684845Methyl 3-hydroxy-5-mercapto-4-methylthiphene-2-carboxylate

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

The acetylthiothiophene of (f) above (10 mmol) was added to 30 ml of 1M potassium hydroxide in methanol. After acidification of the mixture, the mercapto thiophene was obtained, recrystallising from hexane, m.p. 86°-88° C.

出典と根拠

ORDレコード
ord-7076ab0dd12c417cb940f3f574dd7eb8
出典データセット
uspto-grants-1991_08
特許番号
US05041461

反応ノート

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