Ammonia → HCID 14986276、化合物
反応式
C([O:4][CH2:5][C:6]([NH:8][C:9]1[CH:16]=[CH:15][CH:14]=[C:13]([N:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)[C:10]=1[C:11]#[N:12])=[O:7])(=O)C.N>CO>[OH:4][CH2:5][C:6]([NH:8][C:9]1[CH:16]=[CH:15][CH:14]=[C:13]([N:17]2[CH2:18][CH2:19][O:20][CH2:21][CH2:22]2)[C:10]=1[C:11]#[N:12])=[O:7]参加物
4
実験手順
To a solution of 2-(acetoxyacetylamino)-6-morpholinobenzonitrile (3 g) in methanol (200 ml) is added dropwise 28% aqueous ammonia (10 ml). The mixture is stirred at room temperature for 1 hour, and thereafter, the solvent is distilled off under reduced pressure. The resulting residue is recrystallized from ethanol-water to give the title compound (1.4 g) having the following physical properties.
後処理
- distillationthe solvent is distilled off under reduced pressure
- customThe resulting residue is recrystallized from ethanol-water
出典と根拠
- ORDレコード
- ord-92ca61aeed364cfd99a60ebe2e4b3071
- 出典データセット
- uspto-grants-1991_08
- 特許番号
- US05041462
反応ノート
読み込み中…