化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Acid → Indole, 5-bromo-3-(dimethylamino)methyl-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Dimethylamine | HCID 674 | — |
| 反応物 | Formaldehyde | HCID 712 | — |
| 反応物 | 5-Bromoindole | HCID 24905 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | Indole, 5-bromo-3-(dimethylamino)methyl- | HCID 13249 | — |
反応手順
This material was prepared by the method of Procedure 67B from 49.5 g. of 5-bromoindole, 20 ml. of 37% aqueous formaldehyde, 55 ml. of 25% aqueous dimethylamine, 250 ml. of acetic acid and 250 ml. of dioxane; yield 60.6 g., m.p. 154°-156° C. The structure was confirmed by examination of the NMR spectrum.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04234595 |
| 出典データセット | uspto-grants-1980_11 |
| ORD ID | ord-b8d02287528a42eeb37d82ed1423ce24 |
| 出典メモ | uspto-grants-1980_11 |