Hydrochloric Acid → 4,5-Dichloro-2-(trichloromethyl)-1H-imidazole

HRID 224918ノート

反応式

HRID 224918 の反応式
[ClH:1].[Cl:2][C:3]1[C:7]([Cl:8])=[N:6][C:5](=[C:9]([Cl:11])[Cl:10])[N:4]=1>C1(C)C=CC=CC=1>[Cl:2][C:3]1[N:4]=[C:5]([C:9]([Cl:1])([Cl:11])[Cl:10])[NH:6][C:7]=1[Cl:8]

参加物

4

反応物 2

HCID 313Hydrochloric Acid2 回HCID 124825724,5-Dichloro-2-(dichloromethylidene)-2H-imidazole

生成物 1

HCID 124825734,5-Dichloro-2-(trichloromethyl)-1H-imidazole収率 89%

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

Dry hydrogen chloride was passed into a solution of 218 g (1.0 mol) of 4,5-dichloro-2-dichloromethylene-imidazole in about 2 liters of dry toluene until the formation of a precipitate had ended (at least 1 mol). After cooling (the addition of HCl was exothermic), filtering off and drying, 235 g (89% of theory) of 4,5-dichloro-2-trichloromethyl-imidazole of melting point 210° C. (with decomposition) were obtained.

後処理

  1. temperatureAfter cooling (
  2. filtrationfiltering off
  3. customdrying

出典と根拠

ORDレコード
ord-122c496d2bc549e48bffaf283b81140c
出典データセット
uspto-grants-1980_11
特許番号
US04234722

反応ノート

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