Methanol → HCID 53674563、化合物
反応式
[CH3:1][O:2][C:3](=[O:11])[CH:4](Br)[CH2:5][CH2:6][CH2:7][CH2:8][Cl:9].[O-:12][C:13]#[N:14].[K+].[CH3:16][OH:17]>CN(C=O)C>[CH3:1][O:2][C:3](=[O:11])[CH:4]([NH:14][C:13]([O:17][CH3:16])=[O:12])[CH2:5][CH2:6][CH2:7][CH2:8][Cl:9]参加物
5
実験手順
12.78 grams of 2-bromo-6-chlorohexanoic acid methyl ester, 6.08 grams of potassium cyanate and 2.72 grams of methanol were heated under powerful stirring in 70 ml of DMF for 1 hour. The reaction mixture was worked up in the manner described in Example 1. There were obtained 6.29 grams (50.3%) of 6-chloro-2-methoxycarbonylaminohexanoic acid methyl ester with boiling point of 113° C./0.0026 mbar.
出典と根拠
- ORDレコード
- ord-1fecd7af5a044a2aa71e74002a03f9e5
- 出典データセット
- uspto-grants-1980_11
- 特許番号
- US04234744
反応ノート
読み込み中…