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Diethyl Ether → 9b-Allyl-8-methoxy-3-methyl-5,9b-dihydrobenz[e]indoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethyl Ether | HCID 3283 | — |
| 反応物 | Lithium Hydroxide | HCID 3939 | — |
| 反応物 | Picric Acid | HCID 6954 | — |
| 反応物 | Picrate | HCID 4432340 | — |
| 反応物 | 2,3-Dihydro-1h-benzo[e]indole | HCID 11147965 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 9b-Allyl-8-methoxy-3-methyl-5,9b-dihydrobenz[e]indoline | HCID 23330780 | — |
反応手順
The benz[e]indoline IIa was regenerated from the picrate XIVd (X=picric acid) as follows: A mixture of finely powder picrate (10 mmol), 1 N aqueous lithium hydroxide (50 ml), ethanol (20 ml) and ether (100 ml) in a separatory funnel was shaken until all the picrate had dissolved. The ether phase was washed with water and, after drying, was evaporated to dryness to give the free base IIa quantitatively.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04234731 |
| 出典データセット | uspto-grants-1980_11 |
| ORD ID | ord-2a59832b8cf3466b9a85bdd208afeaee |
| 出典メモ | uspto-grants-1980_11 |