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1-Amino-4-hydroxyanthraquinone → 1-Amino-2-bromo-4-hydroxyanthraquinone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Amino-4-hydroxyanthraquinone | HCID 8323 | — |
| 反応物 | 1-Amino-2-bromoanthraquinone | HCID 236895 | — |
| 反応物 | 1-Amino-4-bromoanthraquinone | HCID 627326 | — |
| 溶媒 | 1-Amino-2-hydroxyanthra-9,10-quinone | HCID 3478173 | — |
| 生成物 | 1-Amino-2-bromo-4-hydroxyanthraquinone | HCID 8320 | — |
反応手順
The progress of the bromination may be followed by thin layer chromatography or high pressure liquid chromatography so as to insure that the byproducts, 1-amino-2-bromoanthraquinone and 1-amino-4-bromoanthraquinone, represent less than 1% of the product mixture. This is essential, since hydroxylation of these two products results in 1-amino-2-hydroxyanthraquinone and 1-amino-4-hydroxyanthraquinone respectively. Both products are isolated along with the desired 1-amino-2-bromo-4-hydroxyanthraquinone and therefore give rise to a product with unsatisfactory quality.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04235789 |
| 出典データセット | uspto-grants-1980_11 |
| ORD ID | ord-323b5bf544664fefa041dc236dcb1427 |
| 出典メモ | uspto-grants-1980_11 |