Benzene → HCID 12906828、化合物

HRID 225226

反応式

HRID 225226 の反応式
C1C=CC=CC=1.[CH3:7][C:8]1([CH3:14])[NH:12][CH2:11][CH:10]([CH3:13])[O:9]1.C(N(CC)CC)C.[Br:22][CH:23]([CH2:27][Br:28])[C:24](Cl)=[O:25]>O>[CH3:7][C:8]1([CH3:14])[N:12]([C:24](=[O:25])[CH:23]([Br:22])[CH2:27][Br:28])[CH2:11][CH:10]([CH3:13])[O:9]1

参加物

6

反応物 4

HCID 241Benzene2 回HCID 8471TriethylamineHCID 867902,3-Dibromopropanoyl chlorideHCID 95486Oxazolidine, 2,2,5-trimethyl-

生成物 1

HCID 12906828HCID 12906828、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Fourteen (14 ml.) milliliters of a benzene solution containing 3.5 g. of 2,2,5-trimethyl oxazolidine was added to 25 ml. of benzene and 3.5 g. of triethylamine. Seven and one-half (7.5 g.) grams of 2,3-dibromopropionyl chloride was added dropwise with stirring and cooling in an ice bath. When reaction was complete, the mixture was poured into water and the benzene layer separated, dried over anhydrous magnesium sulfate and the solvent stripped under vacuum. The yield was 5.7 g. of an oil, nD30 =1.5060.

後処理

  1. temperaturecooling in an ice bath
  2. customWhen reaction
  3. customthe benzene layer separated
  4. dry with materialdried over anhydrous magnesium sulfate

出典と根拠

ORDレコード
ord-95a628796b614d20b2674ec6f8d6eea6
出典データセット
uspto-grants-1980_11
特許番号
US04236011

関連ノート

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