Benzene → 2,2-Dimethyl-3-heptanoyl oxazolidine

HRID 225228

反応式

HRID 225228 の反応式
C1C=CC=CC=1.[CH3:7][C:8]1([CH3:13])[NH:12][CH2:11][CH2:10][O:9]1.C(N(CC)CC)C.[C:21](Cl)(=[O:28])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]>O>[CH3:7][C:8]1([CH3:13])[N:12]([C:21](=[O:28])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH2:11][CH2:10][O:9]1

参加物

6

反応物 4

HCID 241Benzene2 回HCID 8471TriethylamineHCID 17313Heptanoyl chlorideHCID 5506972,2-Dimethyl-oxazolidine

生成物 1

HCID 129067982,2-Dimethyl-3-heptanoyl oxazolidine

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Sixteen and one-half (16.5 ml.) milliliters of a benzene solution containing 4.6 g. of 2,2-dimethyl oxazolidine was added to 50 ml. of benzene and 4.1 g. of triethylamine. To this mixture 6 g. of n-heptanoyl chloride was added dropwise with stirring and cooling in an ice bath. The mixture was poured into water and the benzene layer extracted, dried over magnesium sulfate and the benzene removed under vacuum. Yield was 7.5 g. of an oil, nD30 =1.4598.

後処理

  1. temperaturecooling in an ice bath
  2. extractionthe benzene layer extracted
  3. dry with materialdried over magnesium sulfate
  4. customthe benzene removed under vacuum

出典と根拠

ORDレコード
ord-39e1f6b09b71420ca16b1f1bbe89257c
出典データセット
uspto-grants-1980_11
特許番号
US04236011

関連ノート

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