Benzene → 2,2-Dimethyl-3-heptanoyl oxazolidine
反応式
C1C=CC=CC=1.[CH3:7][C:8]1([CH3:13])[NH:12][CH2:11][CH2:10][O:9]1.C(N(CC)CC)C.[C:21](Cl)(=[O:28])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]>O>[CH3:7][C:8]1([CH3:13])[N:12]([C:21](=[O:28])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH2:11][CH2:10][O:9]1参加物
6
実験手順
Sixteen and one-half (16.5 ml.) milliliters of a benzene solution containing 4.6 g. of 2,2-dimethyl oxazolidine was added to 50 ml. of benzene and 4.1 g. of triethylamine. To this mixture 6 g. of n-heptanoyl chloride was added dropwise with stirring and cooling in an ice bath. The mixture was poured into water and the benzene layer extracted, dried over magnesium sulfate and the benzene removed under vacuum. Yield was 7.5 g. of an oil, nD30 =1.4598.
後処理
- temperaturecooling in an ice bath
- extractionthe benzene layer extracted
- dry with materialdried over magnesium sulfate
- customthe benzene removed under vacuum
出典と根拠
- ORDレコード
- ord-39e1f6b09b71420ca16b1f1bbe89257c
- 出典データセット
- uspto-grants-1980_11
- 特許番号
- US04236011
反応ノート
読み込み中…