Pyridinium chloride → 5-[2-(2,4-Difluorophenyl)ethenyl]-2-i-propyl-1,3-benzenediol
反応式
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[CH:9]=[CH:10][C:11]1[CH:16]=[C:15]([O:17]C)[C:14]([CH:19]([CH3:21])[CH3:20])=[C:13]([O:22]C)[CH:12]=1.Cl.N1C=CC=CC=1>>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[CH:9]=[CH:10][C:11]1[CH:12]=[C:13]([OH:22])[C:14]([CH:19]([CH3:20])[CH3:21])=[C:15]([OH:17])[CH:16]=1参加物
3
実験手順
This material was prepared from 1-(2,4-difluorophenyl)-2-(3,5-dimethoxy-4-i-propylphenyl)ethene and pyridine hydrochloride in 44% yield in the same way as described in example 34. 1HNMR (CDCl3, ppm): δ 1.41 (d, J=7.1 Hz, 6H), 3.49 (qint, J=7.1 Hz, 1H), 4.78 (br, 2H), 6.54 (s, 2H), 6.69-7.02 (m, 3H), 7.13 (d, J=16 Hz, 1H), 7.41-7.75 (m, 1H).
出典と根拠
- ORDレコード
- ord-91750fdfd5b84dc69aaed789b293e11e
- 出典データセット
- uspto-grants-2008_01
- 特許番号
- US07321050B2
反応ノート
読み込み中…